Revolutionising the way we treat cancer

We develop a safe and cost effective approach to radiation therapy
to enhance therapeutic efficacy and treatment accessibility
providing improved outcomes and a better quality of life for patients.

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60 %

of all cancer patients receive radiotherapy as part of their treatment plan

Despite huge advancements in treatment planning and dose delivery, a major challenge remains:
Healthy tissues around the treated area absorb part of the radiation, causing side effects.

Radiation oncologists must often decide between delivering a large enough dose to control the tumour and sparing nearby organs from damage. This may lead to poor clinical outcomes and suboptimal survival rates.

We are committed to delivering treatment only where needed

eBeam4Therapy is developing a new approach based on laser plasma accelerator technology to treat deep tissue tumors with very high energy electrons

Benefits

Better
treatment quality

Improved therapy efficacy and patient outcomes

Lower costs for
hospitals and payers

A fraction of the cost relative to particle therapy

Quicker and
safer

More accurate radiotherapy delivery with lower treatment times

Compact, user-friendly machinery

Compatible with existing hospital infrastructures

Where are we now?

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Very high energy electron beams in the ideal energy range for radiotherapy are routinely produced in our facility

national-cancer-institute-BxXgTQEw1M4-unsplash

Study highlights 19% dose reduction to sensitive healthy tissues and better target coverage in prostate cancer relative to X-ray IMRT

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Market pre-validation studies show good acceptance from medical community; First discussions with potential commercial partner

“An enabling technology that will provide a paradigm shift in the medical radiotherapy market”

ebeam4therapy

Our laser–plasma accelerator technology will enable routine delivery of highly energetic electrons in the ideal energy range required for oncologic radiotherapy. By bringing together experts in laser and accelerator science, we will develop a compact, simple, and safe basis for next generation cancer treatment.

eBeam4Therapy is a 3-year project funded by the European Union.

The project aims to to demonstrate the feasibility of laser-plasma technology in the radiotherapy application while paving the way for commercialisation and market entry.

  • Beam optimisation

    Optimise very high energy electron beam parameters for radiotherapy

  • Dosimetric characterisation

    Carry out robust 3D dosimetric characterisation

  • Technology demonstration

    Demonstrate technical feasibility while improving cost effectiveness

  • Go-to-market strategy

    Demonstrate the commercial feasibility and design a strategy to enter the market

  • Investment readiness

    Improve acceptance and satisfy investor requirements

the Team

One of the world’s leading basic research institutions, Weizmann Institute of Science (WIS) comprises 250 experimental and theoretical research groups across five faculties—Biology, Biochemistry, Chemistry, Mathematics and Computer Science, and Physics. Insights that emerge from its labs help provide a fundamental understanding of the human body and the universe, and lead to advances in medicine, technology, and the environment. 

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Professor at the Weizmann Institute of Science, Victor Malka was, until September 2019, a CNRS Research Director at Laboratoire d’Optique Appliquée, and a Professor at Ecole Polytechnique. He has contributed towards several different branches of physics, such as atomic physics, inertial fusion, laser plasma interaction. His work is now devoted to relativistic laser plasma interaction, laser plasma accelerators and related societal applications, in which he has made several breakthrough contributions.

Prof. Dr. Victor Malka

Principal Investigator

Professor at the Weizmann Institute of Science, Victor Malka was, until September 2019, a CNRS Research Director at Laboratoire d’Optique Appliquée, and a Professor at Ecole Polytechnique. He has contributed towards several different branches of physics, such as atomic physics, inertial fusion, laser plasma interaction. His work is now devoted to relativistic laser plasma interaction, laser plasma accelerators and related societal applications, in which he has made several breakthrough contributions.

Eyal Kroupp, PhD in physics, is an expert in plasma physics and an outstanding experimentalist who has been contributing to the underlying technology behind eBeam4Therapy since its conception. His expertise covers the different faces of laser plasma physics, including laser and electron beam diagnostics, targetry development and characterization, optics, electronics, and complex systems.

Dr. Eyal Kroupp

Research Scientist

Eyal Kroupp, PhD in physics, is an expert in plasma physics and an outstanding experimentalist who has been contributing to the underlying technology behind eBeam4Therapy since its conception. His expertise covers the different faces of laser plasma physics, including laser and electron beam diagnostics, targetry development and characterization, optics, electronics, and complex systems.

Anton Golovanov holds a PhD in physics from the Institute of Applied Physics RAS. Anton has an extensive background in theoretical plasma physics and laser-plasma accelerators as well as in numerical simulations of laser-matter interaction. Using his strong theoretical skills, Anton is working towards optimizing the gas target and achieving the desirable parameters of the accelerated electron beam.

Dr. Anton Golovanov

Research Scientist

Anton Golovanov holds a PhD in physics from the Institute of Applied Physics RAS. Anton has an extensive background in theoretical plasma physics and laser-plasma accelerators as well as in numerical simulations of laser-matter interaction. Using his strong theoretical skills, Anton is working towards optimizing the gas target and achieving the desirable parameters of the accelerated electron beam.

Arnaud Courvoisier holds a PhD in physics from the Weizmann Institute of Science as well as a degree in optical engineering from the Institut d'Optique Graduate School. His expertise in the fields of atomic physics, light-matter interaction, optics and optical design are key to the development of the project. In addition to experimental work, Arnaud oversees managerial and administrative aspects of the project in his role as project manager.

Dr. Arnaud Courvoisier

Research Scientist & Project Manager

Arnaud Courvoisier holds a PhD in physics from the Weizmann Institute of Science as well as a degree in optical engineering from the Institut d'Optique Graduate School. His expertise in the fields of atomic physics, light-matter interaction, optics and optical design are key to the development of the project. In addition to experimental work, Arnaud oversees managerial and administrative aspects of the project in his role as project manager.

Aaron Jaffe holds a Bachelor of Laws (LL.B) degree from Tel Aviv University, as well as a Master of Business Administration. Aaron has been admitted to practice law in Israel and New York. Prior to joining Yeda, Mr. Jaffe served as general counsel of two publicly-traded technology companies and was an associate attorney at Yigal Arnon & Co. Aaron and his team at Yeda will be leading the IP management and legal aspects in eBeam4Therapy.

Adv. Aaron Jaffe

General Counsel, Yeda Research & Development

Aaron Jaffe holds a Bachelor of Laws (LL.B) degree from Tel Aviv University, as well as a Master of Business Administration. Aaron has been admitted to practice law in Israel and New York. Prior to joining Yeda, Mr. Jaffe served as general counsel of two publicly-traded technology companies and was an associate attorney at Yigal Arnon & Co. Aaron and his team at Yeda will be leading the IP management and legal aspects in eBeam4Therapy.

rajakrishna kalvala

Dr. Rajakrishna Kalvala is a nuclear engineering expert with a Ph.D. earned at the Indira Gandhi Centre for Atomic Research in Kalpakkam, India. He also holds a master's degree in nuclear engineering from the University of Petroleum and Energy Studies in Dehradun, India, and an undergraduate degree in electronics and communication engineering from JNTU in Hyderabad, India. His extensive knowledge spans various critical areas, including radiation detectors, beam transport, radiation physics, and GEANT4 simulations, which play a pivotal role in advancing the project. His responsibilities encompass designing beam transport systems and performing calculations for radiation dose deposition.

Dr. Rajakrishna Kalvala

Research Scientist

Dr. Rajakrishna Kalvala is a nuclear engineering expert with a Ph.D. earned at the Indira Gandhi Centre for Atomic Research in Kalpakkam, India. He also holds a master's degree in nuclear engineering from the University of Petroleum and Energy Studies in Dehradun, India, and an undergraduate degree in electronics and communication engineering from JNTU in Hyderabad, India. His extensive knowledge spans various critical areas, including radiation detectors, beam transport, radiation physics, and GEANT4 simulations, which play a pivotal role in advancing the project. His responsibilities encompass designing beam transport systems and performing calculations for radiation dose deposition.

Lidan Fridman holds an MSc in Biomedical Engineering from the Technion Institute of Technology. She has expertise in medical applications relying on optical imaging and knowledge in light-tissue interactions, numerical simulations, and optical design. Combining her optical background with her technical skills, Lidan is taking part in building the laboratory and in the development of innovative dosimetry methods.

Lidan Fridman

Doctoral Student

Lidan Fridman holds an MSc in Biomedical Engineering from the Technion Institute of Technology. She has expertise in medical applications relying on optical imaging and knowledge in light-tissue interactions, numerical simulations, and optical design. Combining her optical background with her technical skills, Lidan is taking part in building the laboratory and in the development of innovative dosimetry methods.

Acceler8 Venture Builder

A privately owned venture builder with roots in the European research and industry collaboration landscape. A8 focuses on commercializing research-based innovations born and developed especially in European Research Council (ERC), European Innovation Council (EIC) and European Institute of Innovation & Technology (EIT) funded research.

Acceler8 works on developing innovations towards relevant applications, elevating technology & business readiness levels, carrying out business validation, and productising technologies into a valuable offering. A8 is a strategic R&D actor and business champion that has worked with 100+ researchers and high-tech startups.

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Mr. Antti Heikkilä, CEO of Acceler8, is a business transformation strategist who has ramped up numerous SMEs from scratch. Antti is a highly experienced, top performing co-founder, serial entrepreneur and financial expert with over twenty years of experience in R&D and commercialisation. He has worked 13 years at CERN, establishing international R&D collaborative projects especially at the Large Hadron Collider and supporting partnering of international companies with Big Science Centres (CERN, ESRF, ESO, GSI/ FAIR). Antti is overseeing the commercial work behind eBeam4Therapy while preparing for the next steps beyond the project.

Antti Heikkilä

Commercial Director

Mr. Antti Heikkilä, CEO of Acceler8, is a business transformation strategist who has ramped up numerous SMEs from scratch. Antti is a highly experienced, top performing co-founder, serial entrepreneur and financial expert with over twenty years of experience in R&D and commercialisation. He has worked 13 years at CERN, establishing international R&D collaborative projects especially at the Large Hadron Collider and supporting partnering of international companies with Big Science Centres (CERN, ESRF, ESO, GSI/ FAIR). Antti is overseeing the commercial work behind eBeam4Therapy while preparing for the next steps beyond the project.

Ms. Gabriella Mifsud is a go-to-market strategist with a strong professional background within the pharmaceutical and medical device industry. Gabriella has represented global industry leaders where she has led several successful product and portfolio launches. Over the last two years, she has worked with 20+ academic teams pursuing innovation commercialisation. Gabriella is working on market intelligence gathering, business feasibility validation and route-to-market definition for the laser plasma acceleration technology developed in eBeam4Therapy.

Gabriella Mifsud

Go-to-Market Strategist

Ms. Gabriella Mifsud is a go-to-market strategist with a strong professional background within the pharmaceutical and medical device industry. Gabriella has represented global industry leaders where she has led several successful product and portfolio launches. Over the last two years, she has worked with 20+ academic teams pursuing innovation commercialisation. Gabriella is working on market intelligence gathering, business feasibility validation and route-to-market definition for the laser plasma acceleration technology developed in eBeam4Therapy.

Ms. Júlia Albert Varela, is a life sciences professional with strong international research and communication expertise, acquired through her work both in the academic and industry arena. Julia is experienced in managing and communicating with different stakeholders and presenting innovations to key partners to encourage their engagement and collaboration. In eBeam4Therapy, Julia leads communication & dissemination efforts while building the stakeholder ecosystem required for commercialisation.

Júlia Albert Varela

Communication Expert

Ms. Júlia Albert Varela, is a life sciences professional with strong international research and communication expertise, acquired through her work both in the academic and industry arena. Julia is experienced in managing and communicating with different stakeholders and presenting innovations to key partners to encourage their engagement and collaboration. In eBeam4Therapy, Julia leads communication & dissemination efforts while building the stakeholder ecosystem required for commercialisation.

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